Waters and ACC have united their expertise to tackle the intricacies of Bacterial Endotoxin Testing (BET) head-on. The introduction of an automated approach to BET with the LALbased in vitro endotoxin detection assay, (Pyrochrome®) delivers unparalleled results while significantly reducing manual operations.
It’s far easier to build plates with the Andrew+ robot - and it limits the strain visually, mentally and physically of repeating the same steps over and over again
What is BET and why Automate?
BET is a mandatory validation step for all injectable drugs, biologics, vaccines, medical devices and implants which all need to be guaranteed as non-pyrogenic. Yet, there are significant amounts of pipetting steps involved to accomplish BET assays. As of such, there are a myriad of critical advantages that laboratories can benefit from by harnessing the cutting-edge automation solution « Andrew+™ » from Waters for the Pyrochrome® BET assay, not the least of which are:
- Automating with Andrew+™ significantly minimizes manual pipetting operations
- Workflows are optimized to ensure a smarter, traceable and more efficient process
- Heightened precision and accuracy are achieved for unparalleled consistency
- Reduced tedium and errors
- Diminished ergonomic risks like Repetitive Strain Injuries (RSI)
Together, these advantages directly translate to increased efficiency and throughput that ultimately boost productivity by
redirecting focus towards higher-value tasks.
Minimizing pipetting steps for an improved working environment
Minimum Number of Pipetting Steps
Preparation and Assay Steps | Pyrochrome achieved MANUALLY | Pyrochrome automated with ANDREW+ |
|---|---|---|
Standard Curve Prep | 8 | 2 |
Standard Curve Transfer to Microplate | 15 | – |
Negative Control Transfer to Microplate | 5 | – |
Sample Transfer to Tubes | 6 | 6 |
Sample Transfer to Microplate | 18 | – |
PPC Transfer to Tubes | 6 | 6 |
PPC Prep | 12 | – |
PPC Transfer to Microplate | 18 | – |
Reagent Reconstitution | 4 | 4 |
Reagent Transfer | 56 | – |
Minimum No. Of Pipetting Steps TOTAL | 148 | 18 |
