Bioanalytical solid-phase extraction (SPE) method development often struggles with recovery variability, complex workflows, and the pressure to deliver robust results on tight timelines. This webinar will share how Waters’ Oasis HLB SPE protocols can be optimized to simplify wash/elution conditions to ensure high recovery and cleanliness across diverse analytes using a strategic approach. We will demonstrate how automating these workflows with the Andrew+ Robot reduces manual variability, saves analyst time, and accelerates protocol optimization. Application examples on high-value therapeutics nearing patent expiration, such as Palbociclib and Sitagliptin, will be highlighted.
– Identify practical strategies to overcome recovery variability, matrix effects issues, and development complexity in SPE workflows.
– Learn how to streamline Oasis HLB SPE method development using the 20 Bottle Optimization approach for best-fit SPE protocols across a variety of molecule types.
– See how automation with Andrew+ Pipetting Robot and OneLab Software simplifies SPE method execution, reduces manual variability, and accelerates development timelines.
– Demonstrate robust SPE protocol performance across diverse analytes using real-world applications on high-value therapeutics nearing patent expiration (e.g., Palbociclib, Sitagliptin).
